Single-cell sequencing reveals the landscape of the tumor microenvironment in a skeletal undifferentiated pleomorphic sarcoma patient

Skeletal undifferentiated pleomorphic sarcoma (SUPS) is an invasive pleomorphic soft tissue sarcoma with a high degree of malignancy and poor prognosis.It is prone to recur and metastasize.The tumor microenvironment (TME) and the pathophysiology of SUPS are barely described.Single-cell RNA sequencing (scRNA-seq) provides an opportunity to dissect t

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Platycodon grandiflorum exosome-like nanoparticles: the material basis of fresh platycodon grandiflorum optimality and its mechanism in regulating acute lung injury

Abstract Background Acute lung injury (ALI) is a severe respiratory disease accompanied by diffuse inflammatory responses induced by various clinical causes.Many fresh medicinal plants have shown better efficacy than their dried forms in preventing and treating diseases like inflammation.As a classical Chinese herb, platycodon grandiflorum (PG) has

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